New England Journal of Medicine

July 22, 2020

New data offer insights on COVID treatments for people with cancer

Newly released data on treatment outcomes of people with cancer diagnosed with COVID-19 reveal a racial disparity in access to Remdesivir, an antiviral drug that has been shown to shorten hospital stays, and increased mortality associated with dexamethasone, a steroid that has had the opposite effect in the general patient population.

By Tom Wilemon
Vials with medication and syringe on blue methacrylate table. Horizontal composition. Top elevated view.
July 14, 2020

VUMC studies provide key positive results for COVID-19 vaccine in early-stage clinical trial

An experimental coronavirus vaccine stimulated robust immune responses against SARS-CoV-2, the virus that causes COVID-19, and raised no serious safety concerns in an early-stage clinical trial.

By Leigh MacMillan
October 24, 2019

Article examines need for genotyping after stenting

Genotyping can improve outcomes in patients who require anti-platelet therapy following stent placement to open narrowed or blocked coronary arteries and prevent a heart attack.

By Bill Snyder
October 9, 2019

Vanderbilt health policy expert explains TennCare block grant proposal

Tennessee has made an “opening bid” in its negotiations with the federal government about a block grant that could significantly change how TennCare functions for more than 1 million children and low-income individuals, and making sense of the complex proposal can be tricky.

By Jill Clendening
The study team included, from left, Douglas Johnson, MD, Dan Roden, MD, Javid Moslehi, MD, Joe-Elie Salem, MD, PhD, and Ali Manouchehri, MD.
September 25, 2019

Study identifies targeted therapy’s cardiac risks

After a recent study showed that chronic lymphocytic leukemia patients who received ibrutinib as a frontline treatment had a 7% death rate, a new study offers a clearer picture on the reasons for the deaths.

By Tom Wilemon
September 19, 2019

All-in-one pill helps reduce blood pressure, cholesterol

A single pill containing low doses of three medications to treat high blood pressure and one to lower cholesterol reduced the estimated risk of cardiovascular disease by 25%, according to a VUMC study.

By Craig Boerner
August 14, 2019

All of Us Research Program Takes Aim at Precision Population Health

Scarcely a year after its national launch, the “All of Us” research program, which aims to accelerate the prevention and treatment of disease, has enrolled more than 230,000 research participants — more than a fifth of its recruitment goal of 1 million people. All
By Bill Snyder
February 18, 2019

VUMC study finds helping patients breathe during intubation prevents life-threatening complications

Thousands of Americans die each year during a dangerous two-minute procedure to insert a breathing tube. Now a Vanderbilt University Medical Center (VUMC) study in the New England Journal of Medicine (NEJM) is showing that using bag-mask ventilation, squeezing air from a bag into the mouth for 60 seconds to help patients’ breathing, improves outcomes and could potentially save lives.
By Craig Boerner
October 25, 2018

Combination therapy improves small-cell lung cancer survival

Patients with stage IV small-cell lung cancer lived longer when given the immunotherapy atezolizumab with chemotherapy, setting the stage for what could become the first new treatment approved in decades for this particularly aggressive form of lung cancer.
By Tom Wilemon
October 22, 2018

Antipsychotics ineffective for treating ICU delirium: study

Critically ill patients are not benefiting from antipsychotic medications that have been used to treat delirium in intensive care units (ICUs) for more than four decades, according to a study released today in the New England Journal of Medicine.
By Craig Boerner
March 1, 2018

Time window extended for some stroke surgeries

New research indicates the time window for a thrombectomy following a stroke is longer than previously thought, but how soon the surgery occurs still matters.
By Tom Wilemon
February 27, 2018

Saline use on decline at Vanderbilt following landmark studies

Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released Feb. 27 that are anticipated to improve survival and decrease kidney complications.
By Craig Boerner
February 15, 2018

Team finds stem cell transplant improves scleroderma survival

A new clinical trial by investigators at Vanderbilt University Medical Center (VUMC) and other leading medical centers found that an intensive transplant treatment using the patient’s own stem cells can improve survival and quality of life for patients with advanced scleroderma.
By VUMC News and Communications
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