New England Journal of Medicine

All of Us Research Program Takes Aim at Precision Population Health

Scarcely a year after its national launch, the “All of Us” research program, which aims to accelerate the prevention and treatment of disease, has enrolled more than 230,000 research participants — more than a fifth of its recruitment goal of 1 million people.
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VUMC study finds helping patients breathe during intubation prevents life-threatening complications

Thousands of Americans die each year during a dangerous two-minute procedure to insert a breathing tube. Now a Vanderbilt University Medical Center (VUMC) study in the New England Journal of Medicine (NEJM) is showing that using bag-mask ventilation, squeezing air from a bag into the mouth for 60 seconds to help patients’ breathing, improves outcomes and could potentially save lives.

Combination therapy improves small-cell lung cancer survival

Patients with stage IV small-cell lung cancer lived longer when given the immunotherapy atezolizumab with chemotherapy, setting the stage for what could become the first new treatment approved in decades for this particularly aggressive form of lung cancer.

Antipsychotics ineffective for treating ICU delirium: study

Critically ill patients are not benefiting from antipsychotic medications that have been used to treat delirium in intensive care units (ICUs) for more than four decades, according to a study released today in the New England Journal of Medicine.

Time window extended for some stroke surgeries

New research indicates the time window for a thrombectomy following a stroke is longer than previously thought, but how soon the surgery occurs still matters.

Saline use on decline at Vanderbilt following landmark studies

Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released Feb. 27 that are anticipated to improve survival and decrease kidney complications.

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