Parkinson’s disease

Combining clinical expertise and trial design, David Charles, MD, and Mallory Hacker, PhD, MSCI, are ready to undertake a groundbreaking study on treatment for Parkinson’s. (photo by Donn Jones)

Vanderbilt neurology research duo shares details of new clinical trial that would take aim at slowing or stopping the progression of Parkinson’s disease 

Parkinson’s is best known for manifesting with a tremor, but patients may have up to four “cardinal features” that include muscle rigidity, slowing of movements and balance problems.

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VUMC set to debut focused ultrasound treatment for tremors, Parkinson’s disease

Focused ultrasound treatment is a minimally invasive procedure for the treatment of tremors or Parkinson’s disease performed in an outpatient clinic with MRI as the navigation tool.

Stephen Purcell

It’s been 16 years since sweet-spot brain stimulation slowed Parkinson’s progression for Hermitage man

In 2008 at VUMC there were a group of doctors trying something unheard of on a handful of patients who signed up for their study. Half would receive deep brain stimulation (DBS) surgery in attempt to slow the progression of their early-stage Parkinson’s disease, and the others would not.

VUMC recognized for atypical Parkinsonism care and research

Vanderbilt’s Department of Neurology has been named a CurePSP Center of Care

Study suggests way to relieve cognitive deficits caused by Parkinson’s disease

Vanderbilt research raises the possibility of using DBS to slow the decline of cognitive function, a major source of disability, diminished quality of life, and death in more than three-quarters of patients with Parkinson’s disease.

photo of David Charles and Mallory Hacker

Deep brain sweet spot might be key to halt Parkinson’s

A sweet spot in the deep brain with direct lines of communication to motor regions far out on the cerebral cortex might hold a key to halting the progression of early-stage Parkinson’s disease.

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