PLOS Genetics (journal) Archive — Page 1 of 1

Glowing blue and magenta DNA double helix formed from particles, surrounded by streams of digital numbers and data-like light patterns.
May 29, 2026

AI technique improves cancer gene discovery for breast and prostate cancer

The artificial intelligence model Enformer was retrained with tissue-specific datasets; this “transfer learning” approach outperformed the base model in identifying disease-associated genes.

By Leigh MacMillan
Healthcare professional in a white coat using a tablet beside a translucent digital globe and medical technology interface graphics.
June 17, 2021

Drug allergy labels in medical records power searches for gene-drug associations

By Paul Govern
Portrait of a smiling man wearing a white medical coat over a purple shirt against a brown background.
April 15, 2021

Alzheimer’s study tracks protein located inside cells

New research from Vanderbilt University Medical Center, published recently in the journal PLOS Genetics, suggests an essential role for a somewhat obscure biomolecule and casts light on a potential drug target in Alzheimer’s disease.

By Paul Govern
(Joe Howell / Vanderbilt)
July 11, 2013

Model for MADD mitochondrial disease

A zebrafish model of a severe mitochondrial disease will be useful for developing new therapeutic approaches.

By Leigh MacMillan