respiratory syncytial virus (RSV)

Cryogenic electron microscopy (cryo-EM) resolution of the structure of a respiratory syncytial virus fusion protein (shades of pink) bound to fragments of two antibodies (dark/light and blue/green) designed by the researchers’ protein language model, MAGE.
November 4, 2025

AI can speed antibody design to thwart novel viruses: study

While the study focused on development of antibody therapeutics against existing and emerging viral threats, the implications of the research are much broader.

By Bill Snyder
November 3, 2025

Prescribing with purpose

A Vanderbilt University Medical Center study finds unnecessary antibiotic prescriptions in hospitalized children and highlights opportunity for antibiotic stewardship.

By Chelsea N. Campbell
(Adobe Stock)
August 30, 2025

One shot of RSV vaccine effective against hospitalization in older adults for two seasons

RSV causes substantial seasonal illness during fall and winter in the U.S., with an estimated 100,000-150,000 hospitalizations and 4,000-8,000 deaths.

By Craig Boerner
June 17, 2025

VUMC-led research a step closer to understanding, preventing asthma 

“Findings from this study indicate that children who develop wheezing have different airway characteristics early in life, even before they develop asthma,” said Tina Hartert, MD, MPH.

By Bill Snyder
May 8, 2025

Newer preventive options helping reduce RSV-associated hospitalization rates among infants

For decades no effective preventive options existed, and the tools now exist to prevent severe disease.

By Jessica Pasley
September 4, 2024

RSV vaccine in older people cuts risk of hospitalization

A multicenter study conducted in 19 states between October 2023 and March 2024 demonstrated that RSV vaccination was 75% effective in preventing RSV-associated hospitalizations for adults age 60 and older.

By Bill Snyder
April 29, 2024

New tool helps identify babies at high risk for RSV

A new tool to identify infants most at risk for severe respiratory syncytial virus (RSV) illness could aid pediatricians in prioritizing children under 1 to receive a preventive medication before RSV season (October-April).
By Craig Boerner
August 15, 2023

Study finds most infants receiving ICU-level care for RSV had no underlying medical condition

A Vanderbilt study found that most infants admitted to the intensive care or high acuity unit for respiratory syncytial virus (RSV) infections during fall 2022 were previously healthy and born at term.
By Jessica Pasley
August 4, 2023

Researchers discover antibody that neutralizes both RSV and hMPV

Vanderbilt and Stanford University researchers discovered a potent, cross-neutralizing human monoclonal antibody against the respiratory syncytial virus and human metapneumovirus.
By Anthony Czelusniak
April 24, 2023

Study finds early RSV infection linked to significantly increased risk of asthma in children

A Vanderbilt study has found that RSV infection in the first year of life is associated with a significantly increased risk of asthma in children.
By Nancy Humphrey
March 9, 2023

Study finds RSV may evade vaccines via rapid mutation

A Vanderbilt study concluded that RSV’s ability to mutate rapidly to escape detection by the body’s immune system makes it more challenging to design and develop vaccines that can stop it from spreading.
By Bill Snyder
July 21, 2022

Study explores role RSV plays in later asthma development

A Vanderbilt clinical project will follow 1,950 Middle Tennessee children to determine how genes and the environment interact with RSV infection during the first year of life and contribute to asthma development
By Leah Mann
February 28, 2022

Study finds azithromycin use during RSV not useful in preventing recurrent wheezing, may cause harm

Vanderbilt research on the impact of the antibiotic azithromycin during severe respiratory syncytial virus (RSV) bronchiolitis overwhelmingly support current national bronchiolitis guidelines, which recommend against antibiotics during acute bronchiolitis due to lack of effect on the acute illness.
By Jessica Pasley
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