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Roy Zent Archives

VUMC study finds molecular switch key to repair of kidney damage

Feb. 7, 2024—Researchers at Vanderbilt University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair.

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Vanderbilt investigators land Keck Foundation grant for groundbreaking genetic research

Jul. 3, 2023—Vanderbilt scientists have received a $1.2 million award from the W. M. Keck Foundation for their groundbreaking project, “Genetic Intolerance Patterns as a Treasure Map to Genes that Define Us as Human.”

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The role of integrins in kidney “integrity”

Jan. 13, 2022—Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered.

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Harrison Society researcher discovers key regulator of kidney cell structure

Nov. 4, 2021—New research from Vanderbilt could aid efforts to promote kidney regeneration after injury or to develop engineered organs.

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New insights into kidney development

Apr. 15, 2021—Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function.

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Team tracks integrin’s role in lung function

Feb. 6, 2020—Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered.

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New Physician Science Doctoral Program graduates first student

Feb. 2, 2017—As a fellow in pulmonary and critical care medicine at Vanderbilt University School of Medicine, Bradley Richmond, M.D., saw a lot of patients with chronic obstructive pulmonary disease (COPD), an inflammatory lung disease caused most often by long-term exposure to cigarette smoke.

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Surprising finding by VU team sheds light on fibrotic disease

Jan. 19, 2017—Integrins are membrane proteins made up of combinations of different “alpha” and “beta” subunits that enable cells throughout the body to interact with their surroundings.

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Integrin discovery may lead to better lung treatments

Jan. 8, 2015—Vanderbilt University researchers have made an important advance in understanding lung development, which one day could lead to improvements in treating lung disease in premature infants and adults.

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Photo: Summer research conference

Jul. 31, 2014—Undergraduates from across the country attended a summer research conference at Vanderbilt this week sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases.

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Molecular ‘chat’ holds kidney fibrosis clues

Jul. 10, 2014—A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process.

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New holders of endowed chairs honored

Mar. 21, 2013—Seven Vanderbilt University faculty members named to endowed chairs were honored for outstanding academic achievements March 19 during a celebration at the Student Life Center.

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Recent Stories from VUMC News and Communications Publications

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Hope
Momentum
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