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Vanderbilt Epidemiology Center Archives

Study incorporates genetics with smoking history to identify high-risk smokers for lung cancer screening

Mar. 9, 2021—A study by Vanderbilt researchers that analyzed both smoking history and genetic risk variants for lung cancer supports modifying current guidelines to include additional smokers for lung cancer screening.

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Fibroids and birth outcomes

Sep. 8, 2020—Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance.

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A step toward cancer prevention

Aug. 10, 2020—A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention.

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Appendix cancer survival in young patients varies by race: study

Aug. 6, 2020—The first study of appendiceal cancer patterns and survival by race/ethnicity among patients younger than 50 in the U.S. showed survival disparities.

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Polygenic scores identify those at high cancer risk

Apr. 23, 2020—A team of Vanderbilt researchers constructed polygenic risk scores (PRS) based on genomic variants associated with eight common cancers and concluded they could potentially be used for personalized risk assessments.

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Meat intake and colorectal polyps

Mar. 9, 2020—Red and processed meat intakes are strongly associated with increased risk of sessile serrated polyps, which are not as well studied as conventional adenomas.

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HDL-cholesterol and breast cancer risk

Jan. 23, 2020—Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.

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Potential prostate cancer biomarkers

Sep. 19, 2019—An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk.

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Shu, Zheng receive Vietnam’s top honor for foreign scientists

Aug. 1, 2019—The Vietnamese Ministry of Health has awarded two Vanderbilt epidemiologists the Memorabilia Medal “For the People’s Health” in appreciation for their contributions in helping the nation establish a population-based research program for cancer, diabetes and other non-communicable diseases.

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Asia’s diabetes epidemic preferentially kills women, the middle-aged: study

Apr. 22, 2019—Diabetes has reached epidemic proportions in Asia and has dramatically increased the risk of premature death, especially among women and middle-aged people, a multinational study led by Vanderbilt University researchers has found.

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Asian nations in early tobacco epidemic: study

Apr. 18, 2019—Asian countries are in the early stages of a tobacco smoking epidemic with habits mirroring those of the United States from past decades, setting the stage for a spike in future deaths from smoking-related diseases.

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Team identifies new gene candidates for breast cancer risk

Jun. 28, 2018—Jun. 28, 2018—An international coalition led by scientists at Vanderbilt University Medical Center and the QIMR Berghofer Medical Research Institute in Herston, Australia, has identified 48 candidate susceptibility genes for breast cancer risk, including 14 genes at loci (chromosome regions) not yet reported for breast cancer.

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