Vanderbilt Institute for Infection Immunology and Inflammation (VI4)

color-enhanced cross section of tumor tissue

Study shows cancer vaccine blocks tumor progression at early lesion stage

The findings support further vaccine investigation to make long-term, progression-free survival a reality for more cancer patients.

Bacterial metabolism plays role in staph antibiotic tolerance

Staph is a leading bacterial cause of death from bloodstream, bone and joint infections, in part because of high rates of antibiotic treatment failure.

Cover of the VI4 AiR (Artist-in-Residence) 2022 annual report: B cells, antibodies and strands of free-flowing DNA represent B cell genome modification and the formation of unique antibodies. Illustration by Nadia Kafil, a UT-Austin biochemistry major who participated in the nationwide AiR program in the lab of Columbia University professor Uttiya Basu, PhD.

Vanderbilt Vaccine Center to begin artist-in-residence program this fall

The six-month-long “Visualizing Virology” residency is an extension of the VI4 Artist-in-Residence Program established in 2019 by the Vanderbilt Institute for Infection, Immunology and Inflammation (VI4), and supported by the Burroughs Wellcome Fund.

Expanded space boosts cutting-edge research in infectious diseases and immunology

The Vanderbilt Institute for Infection, Immunology and Inflammation recently debuted state-of-the-art new facilities in Medical Center.

‘Molecular Muse’ exhibit features Artist-in-Residence program’s science-inspired art

The “Molecular Muse” art exhibit on display in Light Hall is a sampling of pieces from the Vanderbilt Institute for Infection, Immunology and Inflammation Artist-in-Residence (VI4-AiR) program, which brings together scientists and artists to create and promote art as a visual science communication tool.

A C. diff bacterium (green) with iron particles in red, shown in a reconstructed electron tomogram from STEM-EDS. (image courtesy of James McBride)

Novel C. diff structures are required for infection, offer new therapeutic targets

Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs.

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