Wei Zheng Archives
Breast cancer genetics: new insights
Feb. 16, 2023—Largest genetic study of breast cancer to date identifies 222 genetic risk loci, 137 genes and multiple signaling pathways associated with risk, providing important new insights.
Ginseng intake and mortality
Jun. 20, 2022—Regular ginseng intake, particularly over a long duration, is associated with decreased risk of death from all causes, Vanderbilt researchers discovered in a large epidemiological study.
Study to evaluate how environment impacts cancer risk
Oct. 21, 2021—Vanderbilt-Ingram Cancer Center is leading an ambitious project to assess the impact of environmental exposures on cancer risk for people living in Southern states.
Structural variants in breast cancer risk genes
Sep. 16, 2021—Vanderbilt epidemiologists conducted in-depth whole genome sequencing of breast cancer risk genes in Black women, who die at higher rates and have more aggressive disease, to discover mutations that may improve testing and treatment selection.
People at high genetic risk for colorectal cancer benefit more from lifestyle changes
May. 13, 2021—People with a high polygenic risk score for colorectal cancer could benefit more at preventing the disease by leading healthy lifestyles than those at lower genetic risk, according to a study by Vanderbilt researchers published in the April issue of The American Journal of Clinical Nutrition.
Zheng named VICC associate director for Population Sciences Research
Apr. 21, 2021—Wei Zheng, MD, PhD, MPH, Anne Potter Wilson Professor of Medicine, has been named associate director for Population Sciences Research at Vanderbilt- Ingram Cancer Center (VICC).
Study incorporates genetics with smoking history to identify high-risk smokers for lung cancer screening
Mar. 9, 2021—A study by Vanderbilt researchers that analyzed both smoking history and genetic risk variants for lung cancer supports modifying current guidelines to include additional smokers for lung cancer screening.
New markers of colorectal cancer risk
Oct. 29, 2020—Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo.
A step toward cancer prevention
Aug. 10, 2020—A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention.
Polygenic scores identify those at high cancer risk
Apr. 23, 2020—A team of Vanderbilt researchers constructed polygenic risk scores (PRS) based on genomic variants associated with eight common cancers and concluded they could potentially be used for personalized risk assessments.
HDL-cholesterol and breast cancer risk
Jan. 23, 2020—Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.
Potential prostate cancer biomarkers
Sep. 19, 2019—An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk.
