Research

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Blood formation and disorders expert Stuart Orkin to present Discovery Lecture March 27

Orkin’s research led to a gene therapy for sickle cell disease and beta-thalassemia; it is the first Food and Drug Administration-approved CRISPR-based gene therapy.

Potential therapeutic for Duchenne muscular dystrophy takes step forward

Positive findings from a clinical trial support further study of the investigational drug ifetroban to treat cardiac complications, the leading cause of death in patients with DMD.

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‘Trajectories’ of poor sleep over time may shorten your life: study

Long-term trajectories of irregular sleep durations outside the optimal range (more or less than the healthy duration of seven to nine hours of sleep per night) increased the risk of death from all causes by as much as 29%.

Virtual reality eases pain, stress for chemotherapy patients: study

The patients exhibited lower heart rates, reported high satisfaction with virtual reality and experienced no feelings of cybersickness.

From left, 2024 Vanderbilt Prize winner Sarah Tishkoff and Vanderbilt Prize Student Scholar Kimberlyn Ellis. (photo by Susan Urmy)

Evolution, genomics and disease: a very special Discovery Lecture

Sarah Tishkoff described her groundbreaking research during a talk titled “African Evolutionary Genomics: Reconstructing Human Evolution and the Genetic Basis of Complex Adaptive Traits.”

VUMC to develop AI technology for therapeutic antibody discovery

The approach will address “bottlenecks” that slow the traditional antibody discovery process, and it aims to make it possible to generate monoclonal antibody therapies against any target of interest.

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