Research

Combining clinical expertise and trial design, David Charles, MD, and Mallory Hacker, PhD, MSCI, are ready to undertake a groundbreaking study on treatment for Parkinson’s. (photo by Donn Jones)

Vanderbilt neurology research duo shares details of new clinical trial that would take aim at slowing or stopping the progression of Parkinson’s disease 

Parkinson’s is best known for manifesting with a tremor, but patients may have up to four “cardinal features” that include muscle rigidity, slowing of movements and balance problems.

Study details genetic architecture of congenital diarrheal disorders in infants

The findings represent a significant advance toward development of more effective, targeted therapies for congenital diarrhea and enteropathies

New gene discoveries target uterine fibroids

The research is another step toward development of targeted therapies aimed at reducing the incidence and medical burden of this common condition.

Integrative approach reveals key inflammatory drivers of severe obesity

Severe obesity — a condition of being 100 pounds or more overweight — has doubled in the United States over the past two decades to 9.2%, with the greatest increases among women and Latino populations.

Castiglione lab discovers horses run faster by ignoring an ancient mutation that says ‘stop’

How did horses overcome this challenge? The answer seems to be by using a genetic trick previously thought to occur only in viruses.

Six Vanderbilt faculty elected fellows of international scientific society

One of the world’s largest multidisciplinary scientific societies, the AAAS also publishes the Science family of journals.

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