Research

A receptor thought to be a cell growth inhibitor actually sends pro-survival signals in small cell lung cancer and is a candidate biomarker for poor prognosis.

Vanderbilt researchers have discovered a role for an inflammatory mediator in diabetic skin infections, suggesting new therapeutic targets for this common complication of diabetes.

Lynne Maquat, PhD, recipient of the 2017 Vanderbilt Prize in Biomedical Science whose work has advanced our understanding of human gene expression, will deliver her Vanderbilt Prize lecture as part of the Flexner Discovery Lecture series on Nov. 29.

In the first large-scale analysis of cardiovascular complications linked to immune checkpoint inhibitors, Vanderbilt researchers have shown that heart and vessel complications include myocarditis, pericarditis, vasculitis and arrhythmias, and that they occur early in the course of treatment.

Stress granules that form in response to cellular stress help cancer cells survive and develop resistance to treatment.

Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.

Increasing a certain signaling molecule prevents the degeneration of retinal cells that are lost in glaucoma, suggesting a new way to treat this disease.