Research

November 17, 2023

Study validates use of VUMC suicide risk model in Navy primary care

A Vanderbilt study found that automated suicide risk prediction models operating on electronic health records could help clinical teams efficiently identify patients for face-to-face suicide risk screening and prevention.

By Paul Govern
T cells (orange) engage with cancer cells (blue). Halle Borowski, an artist and senior at the College of William and Mary, worked with Drs. Mary Philip and Jess Roetman to create this oil painting, inspired by their research, as part of the Vanderbilt Institute for Infection, Immunology, and Inflammation (VI4) Artist-in-Residence program (https://www.artlab-air.com/).
November 17, 2023

Tumor antigens key to improving cancer immunotherapy: study

Vanderbilt researchers are working to better design immune therapies that attack tumors without also attacking healthy normal tissue in patients.

By Bill Snyder
November 16, 2023

Nasty microbe H. pylori has Achilles’ heel

Vanderbilt researchers found that an H. pylori enzyme is essential for colonization of the stomach, suggesting it as a promising therapeutic target for H. pylori infection.

By Paul Govern
November 15, 2023

Study finds many patients don’t seek more health services after receiving genetic screening results

A study by Vanderbilt researchers found that more than half of the patients who receive the results of genetic tests might not be impelled to seek more services than they’re already receiving.

By Paul Govern
Mark Denison, MD, and Xiaotao Lu, MS, are among those on a new list of scientists whose papers have been cited the most frequently by other researchers. (photo by Erin O. Smith)
November 15, 2023

Twelve at Vanderbilt are among world’s highly cited researchers

Twelve current investigators at Vanderbilt University Medical Center and Vanderbilt University are on this year’s list of scientists whose papers have been cited the most frequently by other researchers.

By Bill Snyder
A C. diff bacterium (green) with iron particles in red, shown in a reconstructed electron tomogram from STEM-EDS. (image courtesy of James McBride)
November 15, 2023

Novel C. diff structures are required for infection, offer new therapeutic targets

Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs.

By Leigh MacMillan
November 13, 2023

Study finds antiviral treatment is largely underused in children with influenza

Vanderbilt research finds antiviral medications are underused in young children diagnosed with influenza despite national guidelines supporting their use
By Jessica Pasley
November 13, 2023

Most can lower blood pressure by reducing salt, even those on BP drugs: study

New research shows nearly everyone can lower their blood pressure, even people currently on blood pressure- reducing drugs, by lowering their sodium intake.
By Bill Snyder
November 10, 2023

After 40 years, genetics still surprises VUMC’s Nancy Cox

As she looks back on her 40-plus year career, what surprises Nancy Cox, PhD, an internationally known geneticist at Vanderbilt University Medical Center, is how much progress has been made, and yet how much more there is to learn about the role genetic variation plays in human disease.
By Bill Snyder
November 6, 2023

Children’s antibodies highly potent against COVID-19: study

Reporting Nov. 6 in Cell Reports Medicine, Ivelin Georgiev, PhD, and colleagues demonstrated that antibodies isolated from children’s blood samples displayed high levels of neutralization and potency against variants of the COVID-19 virus, SARS-CoV-2, even when the children had not previously been exposed to or vaccinated against those variants.
By Bill Snyder
November 1, 2023

Pancreas “crosstalk” may influence course of Type 1 and Type 2 diabetes

In the largest study of its kind, researchers at Vanderbilt have identified unexpected alterations in the exocrine tissues of the pancreas that occur in the two major forms of diabetes, and with aging and obesity.
By Bill Snyder
October 31, 2023

Polygenic “scores” may improve cancer screening

Accounting for genetic variability in biomarkers not associated with cancer risk could avoid unnecessary diagnostic procedures, Vanderbilt researchers found.
By Bill Snyder
October 27, 2023

Study discovers role for gut bacteria in host-pathogen competition for nutrients

Vanderbilt research shows that commensal gut microbes impact the host-pathogen competition for iron and has implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients.
By Leigh MacMillan
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