Research

January 20, 2022

Omicron evades some but not all monoclonal antibodies: study

A new study found that several, but not all, of the human monoclonal antibodies used clinically to prevent patients from becoming severely ill from COVID-19 may not be protective against the Omicron variant now sweeping across the United States.

By Bill Snyder
From left, J.Court Reese, Stephanie Moore-Lotridge, PhD, Breanne Gibson, PhD, and Jonathan Schoenecker, MD, PhD, are discovering ways to prevent adverse outcomes in orthopaedic surgery.
January 19, 2022

Study identifies molecular trigger of severe injury-induced inflammatory response

Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure.

By Leigh MacMillan
January 19, 2022

Clinical score can guide PRRT therapy decisions for neuroendocrine tumors

A clinical score system developed by researchers at Vanderbilt-Ingram Cancer Center (VICC) has been validated that can guide peptide receptor radionuclide therapy treatment decisions.

By Tom Wilemon
January 18, 2022

Ensuring the “best possible” medication history

About 80% of hospital admission electronic records were missing a drug prescribed to an older adult, Vanderbilt researchers found, highlighting the need for a multipronged approach to address medication discrepancies and support safe prescribing practices.

By Bill Snyder
January 17, 2022

H. pylori, lipid loss and stomach cancer

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered.

By Leigh MacMillan
January 14, 2022

Vanderbilt biostatisticians launch Cancer-Immu data portal for predicting response to immune checkpoint blockade immunotherapy

A new data portal called Cancer-Immu established by a team of Vanderbilt University Medical Center biostatisticians can help cancer clinicians and researchers predict which patients will respond to immune checkpoint inhibitors.

By Tom Wilemon
January 13, 2022

The role of integrins in kidney “integrity”

Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered.
By Bill Snyder
January 13, 2022

Salmonella overcomes host resistance

The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization.
By Leigh MacMillan
January 13, 2022

Study seeks to refine head and neck cancer treatment options

By Bill Snyder
January 6, 2022

Study explores how bacteria become drug resistant

Vanderbilt researchers have revealed more of the inner-workings of a two-stage “molecular motor” in the cell membrane that enables bacteria to become resistant to drugs.
By Bill Snyder
December 24, 2021

Study of fully vaccinated patients with cancer who had breakthrough COVID-19 shows 13% mortality rate

New research finds that fully vaccinated patients with cancer who had breakthrough COVID-19 infections remained at high risk for hospitalization and death.
By Tom Wilemon
December 21, 2021

Study finds apixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stroke prevention, reduced bleeding complications

By Jill Clendening
December 20, 2021

“Atlas” of lung development may aid efforts to heal premature lungs

Researchers at Vanderbilt University Medical Center have constructed a single-cell “atlas” of lung development that tracks multiple cell types over time.
By Bill Snyder
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