Research

A clue to an adverse drug event in children

Considering metabolic (CYP2D6) enzyme activity score and patient age may aid in determining an individual’s risk for an adverse event with administration of the anti-arrhythmic drug propafenone.

Stomach

Molecular ‘switch’ may illuminate stomach disorders

An international team that included researchers from Vanderbilt University Medical Center has discovered a molecular switch that induces rapid proliferation of zymogen granule-secreting chief cells in the stomach to regenerate damaged tissue.

Andy Weiss, PhD, Caitlin Murdoch, PhD, and colleagues have characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins.

Study identifies first cellular “chaperone” for zinc, sheds light on worldwide public health problem of zinc deficiency

A team led by Vanderbilt researchers has described and characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins.

From left, Raymond C. Harris, MD, Shirong Cao, MD, PhD, Ming-Zhi Zhang, MD, MSc, and colleagues are studying the role of inflammation in obesity.

Study sheds light on the dark side of obesity

Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity.

VUMC-led study finds Moderna COVID vaccine safe and effective for children

Report lays out solution for pandemic patient privacy

Health information privacy experts at Vanderbilt University Medical Center, the University of Texas at Dallas and IBM have collaborated on a public case reporting framework keyed to the dynamics of pandemics.

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