Research

HIV cell

Key factors in HIV-1 replication

HIV-1, the virus that causes AIDS, exploits inositol phosphates in T cells to aid its own assembly and maturation — suggesting that targeting inositol phosphate binding could inhibit HIV-1 replication.

Convalescent plasma improved survival in COVID-19 patients with blood cancers

Treatment with convalescent plasma vastly improved the survival rate of patients hospitalized for COVID-19 who also had hematologic malignances that compromise the immune system, according to new data released by the COVID-19 and Cancer Consortium (CCC19).

New clue to postural tachycardia

Insight into the pathophysiology of an enigmatic and debilitating disease suggests new treatment approaches.

Jennifer Pilat, left, Sarah Short, PhD, Christopher Williams, MD, PhD, and colleagues are studying a biomarker for assessing disease severity and cancer risk in patients with inflammatory bowel disease.

Potential biomarker for IBD severity, cancer risk identified

A selenium transport protein produced in the colon may be a novel biomarker for assessing disease severity and cancer risk in patients with inflammatory bowel disease.

Gene network for leukemia factor

A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment.

Christopher Hughes, MD, left, Pratik Pandharipande, MD, MSCI, and colleagues are studying two drugs recommended for patients receiving mechanical ventilation in the ICU.

Study finds recommended ICU sedatives equally safe, effective

Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia.

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