Research

May 24, 2021

Analysis reveals macrophages associated with kidney cancer recurrence

A white blood cell, the TREM2/APOE/C1Q-positive macrophage, has been identified as a potential biomarker to predict recurrence of the most common type of kidney cancer and as a possible target for drug development.

By Tom Wilemon
May 20, 2021

New clue to lung scarring

Vanderbilt neonatology team pinpoints signaling pathways involved in the progressive lung fibrosis that occurs in rare genetic diseases.

By Bill Snyder
Insulin in vials
May 20, 2021

Beta cell regeneration

Vanderbilt researchers dissected the complex microenvironment of the pancreatic islet to discover the signals that drive beta cell regeneration — as a possible treatment for diabetes.

By Leigh MacMillan
May 20, 2021

Type 2 diabetes medication shown to benefit asthma patients

Type 2 diabetes patients who also have asthma are benefitting from a diabetes medication, typically given to help the pancreas produce more insulin, that also improves asthma symptoms and may reduce lung and airway inflammation.

By Craig Boerner
May 20, 2021

VUMC is pacesetter for national aspirin study

According to an innovative large-scale clinical trial reported last week in the New England Journal of Medicine, a single daily baby aspirin (81 mg) or a single daily adult aspirin (325 mg) are equally safe and effective for prevention of adverse cardiovascular events for patients with established atherosclerotic cardiovascular disease.

By Paul Govern
May 13, 2021

People at high genetic risk for colorectal cancer benefit more from lifestyle changes

People with a high polygenic risk score for colorectal cancer could benefit more at preventing the disease by leading healthy lifestyles than those at lower genetic risk, according to a study by Vanderbilt researchers published in the April issue of The American Journal of Clinical Nutrition.

By Tom Wilemon
May 12, 2021

Nominations sought for Vanderbilt Prize Student Scholar

Nominations for the 2021 Vanderbilt Prize Student Scholar are now open. The deadline is June 1.
By Bill Snyder
May 6, 2021

VUMC to lead national study to treat severe COVID complications

The Vanderbilt Institute for Clinical and Translational Research (VICTR) has been awarded a major federal grant to lead a national trial of treatments targeting the Renin Angiotensin Aldosterone System (RAAS) in patients hospitalized with COVID-19.
By Bill Snyder
May 6, 2021

Study finds that regulatory protein prevents signaling that triggers cell death

A protein implicated in neurodegenerative diseases including amyotrophic lateral sclerosis prevents the activation of an innate immune response that leads to cell death, Vanderbilt researchers have discovered.
By Leigh MacMillan
May 4, 2021

New strategy to treat brain bleeding

Vasorelaxing peptides could offer a promising therapeutic strategy for reducing the neurological deficits caused by subarachnoid hemorrhage-induced cerebral blood vessel constriction.
By Leigh MacMillan
May 3, 2021

Strength in numbers

Voluntary data sharing across a region’s health systems and ambulatory care practices is important for measuring and improving health care quality and safety, Vanderbilt researchers report.
By Paul Govern
April 29, 2021

Genetic ancestry and hypertension risk

Racial disparities in hypertension risk are due in part to genetic differences between ancestries, Vanderbilt investigators find in a study of participants in the Million Veteran Program.
By Bill Snyder
April 29, 2021

A compound to counteract aging?

A compound that increases lifespan in yeast is offering clues to pharmacological approaches that might slow the aging process and improve health.
By Leigh MacMillan