Research

June 13, 2019

Cardiac toxicity risk factors identified with relapsed multiple myeloma therapy

More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study published June 12 in the Journal of Clinical Oncology.

By Tom Wilemon
June 13, 2019

Eng named to GI cancer leadership position at VICC

Cathy Eng, MD, a national and international leader in gastrointestinal medical oncology, is joining Vanderbilt-Ingram Cancer Center (VICC).

By Tom Wilemon
From left, Alexander Gelbard, MD, Suman Das, PhD, and Simon Mallal, MBBS, are among a team of researchers searching for the cause of a rare airway disease that almost exclusively affects adult, Caucasian women.
June 13, 2019

Study seeks to expand treatment options for rare airway disease

Armed with $1.2 million in funding from the National Heart, Lung and Blood Institute (NHLBI), researchers at Vanderbilt University Medical Center are searching to understand the cause of a rare airway disease in hopes of developing better treatments.

By Kelsey Herbers
June 12, 2019

Steroid binding to metabolic enzyme

Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.

By Bill Snyder
June 10, 2019

Cell-cell signals in developing heart

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.

By Leigh MacMillan
Research assistant Mahsa Majedi loads reagent used in DNA sample preparation in the genomics lab. She is part of a team of more than a dozen people at VUMC who are “sprinting” to develop — within 90 days — an antibody-based treatment to stop the spread of the Zika virus.
June 6, 2019

VUMC joins international effort to speed vaccine development

VUMC has joined an international effort to streamline and accelerate development of vaccines and other treatments against a growing worldwide surge of deadly and debilitating viral infections.

By Bill Snyder
June 6, 2019

Mouth microbes and colorectal cancer

Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.
By Leigh MacMillan
June 6, 2019

Treating core Rett syndrome symptoms

A new study published in Neurology reports the drug trofinetide has proven safe and effective in treating core symptoms of Rett syndrome in female children and adolescents.
By Kelsey Herbers
June 6, 2019

Study sheds light on importance of comprehension when obtaining consent

Bioethics study focuses on comprehension of informed consent for research
By Doug Campbell
May 29, 2019

Study details regulation of a multi-drug transporter

P-glycoprotein distinguishes between chemicals that it will expel from a cell and inhibitors that block its action.
By Leigh MacMillan
May 16, 2019

Flu’s “hidden target” may lead to universal vaccine: study

Researchers at Vanderbilt University Medical Center and the Scripps Research Institute have discovered a “hidden target” on the surface of the hypervariable influenza A virus that could lead to better ways to prevent and treat the flu.
By Bill Snyder
May 9, 2019

Line placement better with ultrasound

Using ultrasound to place arterial lines reduces the need for surgical access and improves arterial line location, Vanderbilt researchers have found.
By Paul Govern
May 9, 2019

Frog fungus fights back

Louise Rollins-Smith and colleagues are exploring how a deadly fungus counters the amphibian immune response and contributes to declining worldwide amphibian populations.
By Leigh MacMillan
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