Research Archive — Page 87 of 139

Computer-generated molecular rendering of a spherical viral particle, with purple and green surface components surrounding yellow and red internal structures.
October 6, 2020

Early steps in reovirus replication

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found.

By Leigh MacMillan
Open orange prescription bottle spilling green-and-white capsules onto a white surface.
October 5, 2020

Treating appendicitis with antibiotics instead of surgery may be good option for some, but not all, patients

Antibiotics instead of surgery may be a good choice for some, but not all, patients with appendicitis, according to results from a study reported today in the New England Journal of Medicine.

By Nancy Humphrey
VUMC NEWS logo in white lettering inside a cyan and yellow outlined square on a blue gradient background.
October 5, 2020

Nominations sought for 2021 Vanderbilt Prize in Biomedical Science

Nominations for the 2021 Vanderbilt Prize in Biomedical Science are now being accepted. The nomination deadline is Dec. 11.

By Bill Snyder
Stylized blue anatomical illustration of two kidneys connected to the central blood vessels.
October 5, 2020

Clue to diabetic kidney disease

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication.

By Sarah E. Glass
Multiple sagittal brain MRI scans arranged in a radiology film layout, with small technical labels throughout.
October 1, 2020

Pinpointing brain changes in psychosis

Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment.

By Leigh MacMillan
Silver medical-alert necklace with a tag labeled “PENICILLIN ALLERGY” and “SEE WALLET CARD,” alongside a medical emblem.
October 1, 2020

Genes spell penicillin allergy risk

Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction.

By Paul Govern