Research

June 10, 2024

Vanderbilt researchers establish biomedical informatics training program in Mozambique

Building sustainable biomedical informatics training and research capacity to address gaps in Mozambique’s national HIV response will help the country leverage newer data-driven and genetics-based approaches for personalized HIV care and molecular epidemiology of the disease.

By Kristen Centers
Brooke Emerling, PhD, and Raymond Blind, PhD (seated, in foreground) at a 2023 scientific symposium they organized. Standing next to Blind is Hua Ya, PhD, from the City of Hope Comprehensive Cancer Center. Behind him in the light blue shirt is Emilio Hirsch, PhD, from the University of Torino, Italy.
June 7, 2024

Discovery raises hopes for new cancer therapy

The study connected the Hippo signaling pathway to phosphoinositides, a particular type of lipid, or fat molecule, which regulates cell functions that are critical in cancer, obesity and diabetes.

By Bill Snyder
June 5, 2024

A novel astrocyte cell in the retina: study

A full understanding of retinal cell types and their functions could point to novel therapeutic targets for diseases that affect the visual system, such as glaucoma — a leading cause of blindness for people over age 60.

By Leigh MacMillan
Eunyoung Choi, PhD, and James Goldenring, MD, PhD. (photo by Erin O. Smith)
June 4, 2024

Grant funds research for therapies to prevent stomach cancer

The funds will help launch a clinical trial in the U.S. with one of the therapies and compare it with another therapy from an ongoing clinical trial in Japan.

By Tom Wilemon
Graduate student Taralynn Mack, left, pipettes a sample while Alexander Bick, MD, graduate student Hannah Poisner, and Celestine Wanjalla, MD, PhD, look on.
June 4, 2024

Research raises hope for treating potentially lethal blood condition

Roughly 1 in 10 people over age 70 will develop CHIP, an explosive, clonal growth of abnormal blood cells that increases risk of blood cancers and death from cardiovascular, lung and liver disease.

By Bill Snyder
Photo caption: Jonathan Mosley, MD, PhD, left, Scott Borinstein, MD, PhD, John Shelley, and Vivian Kawai, MD, MPH, are studying how genetic variation not related to disease affects clinical decisions. (photo by Susan Urmy)
June 3, 2024

Genetic variation associated with low white blood cell count impacts clinical decisions

People whose white blood cell levels are near the edge of the “healthy” reference range will hit a clinical decision point that has consequences such as diagnostic procedures and altered treatments.

By Leigh MacMillan
May 31, 2024

VUMC-led team reports potential new way to stimulate weight loss

Researchers at Vanderbilt University Medical Center and the VA Tennessee Valley Healthcare System have demonstrated in a small clinical study that “turning up the heat” on fat may help people lose weight and reduce their risk of obesity-related cardiovascular and metabolic disease.
By Bill Snyder
May 31, 2024

Antibodies may aid effort to fight influenza B: study

The findings reported in the journal Immunity support the development of a monoclonal antibody for prevention and treatment of influenza B — and will help guide efforts to develop a universal influenza vaccine.
By Bill Snyder
May 30, 2024

NIH awards $4.2 million for AI patient assessment

Tkaczyk and collaborators will assemble a database of more than 11,000 photographs and associated clinical information from diverse patient populations at five centers: Fred Hutchinson Cancer Center, Mayo Clinic, NIH, University of Pennsylvania and VUMC.
By Paul Govern
May 30, 2024

Speakers share history of hereditary cancers at scientific retreat 

Speakers at the Vanderbilt-Ingram Cancer Center 25th Annual Scientific Retreat detailed the history of hereditary cancer discoveries and gave overviews about ongoing research. 
By Tom Wilemon
May 29, 2024

Kristin O’Grady receives $2.4 million for multiple sclerosis imaging studies

The awards will support O’Grady’s application of structural and functional magnetic resonance imaging to better understand symptoms and track MS progression in the lower spinal cord.
By Bill Snyder
May 28, 2024

Jennifer Gordetsky honored for her history of urology research

Jennifer Gordetsky, MD, believes the most important part of medical history is making sure our mistakes are not forgotten
By Bill Snyder
May 21, 2024

NIH grant supports effort to build expertise in genetic epidemiology research in Vietnam

V2-GENE, the Vanderbilt-Vietnam Genetic Epidemiology Training Program, will develop a team of researchers and educators to lead genetic epidemiology research of noncommunicable diseases across the lifespan in Vietnam.
By Leigh MacMillan
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