February 22, 2022

Internal proposals accepted for NIH S10 shared equipment grants; deadline is April 1

Program Overview

The NIH S10 Instrumentation program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instrumentation or an integrated system. Types of instruments supported by S10 funding include, but are not limited to X-ray diffraction systems, nuclear magnetic resonance (NMR) and mass spectrometers, DNA and protein sequencers, biosensors, electron and confocal microscopes, cell-sorters, and biomedical imagers.

VUMC investigators who intend to apply to either of the S10 programs below should submit an internal proposal for review. An internal proposal is required for all projects and will be used to arrange matching funds and letters of support. Proposals submitted in collaboration with an SOM core facility or shared resource will be prioritized for matching funds.

Shared Instrumentation Grant (SIG) Program:

 High-End Instrumentation (HEI) Grant Program:

Note: VUMC will not qualify for the Basic Instrumentation Grant (BIG) program (PAR-22-081) 

VUMC Internal Application Process

Submit a VUMC internal proposal by April 1 via https://redcap.link/s10program.  Late submissions may be ineligible for matching funds.  Investigators are strongly encouraged to read the appropriate RFA(s) and guidance document prior to submission.

Investigators should submit a brief expression of intent to amy.f.martinez@vumc.org prior to starting an internal application. Include PI, partnering core, and brief equipment description (2-3 sentences). Expressions of intent will be used to assess for scientific overlap and ensure that VU and VUMC do not prepare competing proposals.


VUMC investigators: Contact amy.f.martinez@vumc.org with any questions about the program requirements, eligibility or institutional process.

VU investigators: Find more information about the internal proposal process on the VU S10 site. Please direct any questions to: