Bill Snyder Archive — Page 41 of 121

Illustration of red blood cells and several white blood cells suspended in a red bloodstream.
September 16, 2021

‘Pre-conditioning’ restores immune tolerance

A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered.

Green-gloved laboratory worker holds two small tubes containing clear liquid over a blurred lab coat.
September 8, 2021

VUMC antibodies help neutralize two deadly viruses: study

Vanderbilt researchers have isolated monoclonal antibodies that prevent severe illness and death caused by two emerging and deadly viruses called Nipah and Hendra.

The team studying tumor suppressor protein p53 includes, from left, Jennifer Pietenpol, PhD, and Lindsay Redman-Rivera.
September 2, 2021

Discovery offers insight for development of cancer therapies targeting mutant p53

Vanderbilt researchers have discovered that aneuploidy (an abnormal number of chromosomes) drives malignant phenotypes in cells expressing mutant p53, a tumor suppressor protein that is mutated in more than half of all human cancers.

Jim Jackson poses in a hospital clinic hallway, wearing a dark blazer over a blue-and-white checkered shirt.
September 2, 2021

A leading authority in ICU-related depression and PTSD, Jim Jackson’s skills have proven especially critical to helping patients during the pandemic

“The last year has been so traumatizing and hard, but to use the skills and knowledge that we have been developing to good effect in the service of others during this difficult season has been meaningful.”

Green-gloved laboratory worker holds two small tubes containing clear liquid over a blurred lab coat.
August 20, 2021

COVID-19 antibody ‘cocktail’ discovered at VUMC protects chronically ill: study

A monoclonal antibody cocktail against the COVID-19 virus discovered at Vanderbilt University Medical Center and developed by AstraZeneca reduced the risk of symptoms in a study of immunocompromised and chronically ill adults later exposed to the virus by 77%, the company announced today.

Medical illustration of a blood vessel narrowing from fatty plaque buildup, with red blood cells in the bloodstream and enlarged spherical particles in the foreground.
August 19, 2021

Potential protection from atherosclerosis

Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins.