Leigh MacMillan

The study could suggest ways to promote the transport of phospholipids and cholesterol out of macrophages, immune system cells that play key roles in all stages of atherosclerosis development.
September 15, 2022

Study suggests new mechanism for lipid transporter

A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought.

By Leigh MacMillan
September 13, 2022

Cancer registries and sarcoma research

The number of sarcoma research studies that use the two largest U.S. cancer registries is increasing, but over one-third of studies that asked the same research question reported conflicting findings.

By Leigh MacMillan
September 12, 2022

Enhancing innate immunity in the lung

Vanderbilt researchers show that a TLR4 agonist improves lung immune response and survival in a mouse model of bacterial pneumonia, supporting the development of this drug to protect against pneumonia in hospitalized patients.

By Leigh MacMillan
Luc Van Kaer, PhD, left, Luke Postoak and colleagues have identified a protein that is key to the “education” of immature T cells in the thymus.
September 1, 2022

Study identifies key player in T cell “education”

New Vanderbilt research could inform therapeutic strategies for enhancing thymic function when desired — such as during aging, recovery from radiation therapy or chemotherapy, or other conditions that reduce T cell output.

By Leigh MacMillan
August 30, 2022

A new mechanism for lupus

Vanderbilt researchers describe a new mechanism for the most common form of lupus and suggest a new treatment approach to this autoimmune disease.

By Leigh MacMillan
August 29, 2022

Blood cancer progression

Vanderbilt researchers used single-cell technologies to explore the accumulation of mutations during blood cancer progression, which could help identify strategies for preventing leukemia before it occurs.

By Leigh MacMillan
August 25, 2022

Vanderbilt researchers discover how gut inflammation leads to bone loss

Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss.
By Leigh MacMillan
August 24, 2022

Kelley Colvin is passionate about finding employment opportunities for adults with disabilities. Under his leadership, VUMC has become a model for success.  

“His dedication and time have resulted in, and will continue to result in, employment opportunities for adults with disabilities at Vanderbilt University Medical Center."
By Leigh MacMillan
August 17, 2022

Researchers discover how salt increases blood pressure

A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension.
By Leigh MacMillan
August 15, 2022

Mitochondria and retinal degeneration

Vanderbilt researchers have developed a new cellular model for exploring mitochondrial dysfunction in age-related macular degeneration, the leading cause of blindness in people over 65.
By Leigh MacMillan
August 11, 2022

Genotype-specific blood counts

Vanderbilt researchers report genotype-specific reference ranges to improve interpretation of laboratory blood results in African Americans with a common gene variant that lowers white blood cell counts.
By Leigh MacMillan
August 2, 2022

Targeted cancer drug during pregnancy

The targeted cancer therapy alectinib was safe as a treatment for lung cancer during two pregnancies in a patient with non-small cell lung cancer, according to a case report from Vanderbilt physicians.
By Leigh MacMillan
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