The drug ent-verticilide reduced A-fib incidence and duration in an animal model, suggesting it may be a viable therapeutic option.

Vanderbilt researchers used novel MRI methods to noninvasively quantify measures of neurofluid circulation and found that hypertrophy of a site of cerebrospinal fluid egress may be related to amyloid-beta retention in Alzheimer’s disease.

Detailed studies of the enzymatic properties of PNPLA1 support the requirement for this protein in skin barrier formation.

A machine learning method based on neural networks outperformed a mutational scanning model at identifying disease-causing mutations in an Alzheimer’s disease protein, suggesting the method could be useful for facilitating therapeutic design.

Vanderbilt research finds that GLP1 receptor agonists — a class of diabetes medications — are associated with fewer major adverse cardiovascular events than another type of diabetes drug (DPP4 inhibitors) in older veterans with no prior heart disease.

Vanderbilt researchers identified optimal MRI parameters for estimating the severity of polycystic kidney disease, a common inherited disorder that can lead to end-stage renal failure.