Leigh MacMillan Archive — Page 13 of 84

A C. diff bacterium (green) with iron particles in red, shown in a reconstructed electron tomogram from STEM-EDS. (image courtesy of James McBride)
November 15, 2023

Novel C. diff structures are required for infection, offer new therapeutic targets

Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs.

Randika “Randy” Perera, PhD, left, Wenhan Zhu, PhD, Walter Chazin, PhD, Luisella Spiga, PhD, Ryan Fansler and colleagues discovered that beneficial bacteria in the gut impact the competition that occurs between host cells and pathogens for the essential nutrient iron. (photo by Erin O. Smith)
October 27, 2023

Study discovers role for gut bacteria in host-pathogen competition for nutrients

Vanderbilt research shows that commensal gut microbes impact the host-pathogen competition for iron and has implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients.

Alyssa Hasty, PhD, left, Jeffrey Rathmell, PhD, and Kamran Idrees, MD, MSCI, are part of a multidisciplinary team that received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to study the connection between obesity and cancer. Team members not pictured include Kathryn Wellen, PhD, Liza Makowski, PhD, and Kathryn Beckermann, MD, PhD.
October 24, 2023

Vanderbilt-led team receives 2023 Endeavor Award from The Mark Foundation for Cancer Research

A multidisciplinary team of investigators has received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to support four closely linked projects exploring the fundamental mechanisms that drive the obesity-cancer connection,

Vivian Weiss, MD, PhD, center, George Xu, left, and Matthew Loberg led a multidisciplinary study that identified a molecular signature for aggressive thyroid cancer, which could help guide treatment approaches for patients. (photo by Susan Urmy)
September 25, 2023

Researchers discover molecular signature for aggressive thyroid cancer

A Vanderbilt study found that a molecular signature that predicts aggressive thyroid cancer could help guide treatment approaches for patients.

September 19, 2023

Flavia Atkins brings caring and leadership to the patients she guides as a health care navigator

She takes pride not only in guiding patients on their health care journeys but also in serving as a resource who is always available to her fellow navigators

September 14, 2023

Bone metabolism changes with aging

Vanderbilt researchers have detailed how aging alters the metabolism of bone-forming cells, which could contribute to age-related osteoporosis.