Understanding the inflammatory characteristics of subtypes of chronic rhinosinusitis with polyps should assist with selection of effective therapies, Vanderbilt researchers report.

A broad bioinformatics approach revealed that Hedgehog signaling is upregulated in dedifferentiated liposarcoma, suggesting this pathway may be an early indicator of poor prognosis and a potential therapeutic target.

Vanderbilt research finds that female health care workers were more likely to leave or intend to leave the profession compared to male health care workers during the COVID-19 pandemic.

New research shows that about half of pediatric patients who died of sepsis over the past 20 years at Vanderbilt University Medical Center had evidence of an inflammatory state called persistent inflammation, immunosuppression and catabolism syndrome.

Dietary magnesium depletion in a mouse model activated inflammatory pathways and molecules that promote hypertension, suggesting that increased magnesium consumption may be beneficial for reducing the prevalence of hypertension.

Genetic mosaicism — when the body’s cells do not all have the same genetic makeup — could generate variants previously thought to be spontaneous in genetic disease, and detecting parental mosaicism could clarify recurrence risk for future children.