Leigh MacMillan

September 20, 2024

Fever drives enhanced activity, mitochondrial damage in immune cells

The mechanistic understanding of how cells respond to heat could explain how chronic inflammation contributes to the development of cancer.

By Leigh MacMillan
September 4, 2024

Bacterial metabolism plays role in staph antibiotic tolerance

Staph is a leading bacterial cause of death from bloodstream, bone and joint infections, in part because of high rates of antibiotic treatment failure.

By Leigh MacMillan
August 22, 2024

Vanderbilt Bedford Hospital earns fourth consecutive “A” safety rating from The Leapfrog Group 

The national distinction recognizes VBH’s work to safeguard patients from preventable harm and errors.
August 16, 2024

Rare diseases point to connections between metabolism and immunity

Science Immunology study suggests a new class of inborn errors of immunometabolism and could improve care for patients with these complex diseases.

By Leigh MacMillan
August 7, 2024

Epigenetic change to DNA associated with cancer risk in ‘multi-omics’ study

The new study identifies 4,248 CpG sites associated with the risk of seven different types of cancer: breast, colorectal, renal cell, lung, ovarian, prostate and testicular germ cell cancers.

By Leigh MacMillan
Three-dimensional imaging of kidney tubules (yellow and green noodle-like structures) under low potassium conditions, which puts the kidney into a state of metabolic overdrive and causes cardiovascular problems.
August 5, 2024

Low potassium ‘turns on’ kidney proximal tubule: study

A kidney protein that responds to low levels of blood potassium — which can cause high blood pressure and cardiovascular problems — may be a target for new therapeutics.

By Leigh MacMillan
July 26, 2024

VUMC establishes Essentials in Quality Improvement Certificate

July 25, 2024

Aspirnaut Summer Research Program symposium set for July 30

The presentations will be held from 10 a.m. to 3 p.m. in room 202 Light Hall and are open to the public. 
July 8, 2024

GeneMAP discovery platform will help define functions for ‘orphan’ metabolic proteins 

The combination of genomics and metabolism identified a long-sought mitochondrial choline transporter.
By Leigh MacMillan
June 21, 2024

Salmonella bacteria ‘steal’ nutrients from gut’s resident microbes

The discovery could point to novel strategies for treating food poisoning and other types of gastroenteritis.
By Leigh MacMillan
June 12, 2024

Obesity-cancer connection discovery suggests strategies for improving immunotherapy 

The study reported in the journal Nature provides a mechanistic explanation for the “obesity paradox” — that obesity can contribute to cancer progression but also improve response to immunotherapy.
By Leigh MacMillan
June 11, 2024

“Tic Me Out to the Ballgame” at Nashville Sounds on July 6 to benefit Tourette support group 

Use the QR code on the flyer below, and a portion of the ticket purchase will be donated to the Middle Tennessee Tourette Syndrome support group.
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