Leigh MacMillan

February 20, 2020

Transporter mutation alters cell energy

A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered.

By Leigh MacMillan
February 12, 2020

Allergic diseases expert Locksley set for Discovery Lecture

Richard Locksley, MD, director of the Sandler Asthma Basic Research Center at the University of California, San Francisco, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 20.

By Leigh MacMillan
February 10, 2020

Imaging breast cancer cell size

A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.

By Leigh MacMillan
February 6, 2020

Powering H. pylori pathogenesis

Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer.

By Leigh MacMillan
February 6, 2020

New tool probes gene regulation

Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation.

By Leigh MacMillan
January 28, 2020

Imaging nerve regeneration

Diffusion MRI may provide a noninvasive approach to assess nerve regeneration and distinguish successful from unsuccessful repairs earlier.

By Leigh MacMillan
January 27, 2020

A new contributor to atherosclerosis

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.
By Leigh MacMillan
January 23, 2020

Insights on diabetic retinopathy

A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report.
By Leigh MacMillan
January 23, 2020

HDL-cholesterol and breast cancer risk

Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy.
By Leigh MacMillan
January 22, 2020

VUMC’s Capra, Bastarache set for Jan. 30 Cutting-Edge Discovery Lecture

The intersection of genetics and electronic health records will be discussed by two Vanderbilt University researchers during a Cutting-Edge Discovery Lecture on Thursday, Jan. 30. The lecture will begin at 4 p.m. in 208 Light Hall.
By Leigh MacMillan
January 13, 2020

Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.
By Leigh MacMillan
January 13, 2020

Zinc uptake by a deadly pathogen

The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.
By Leigh MacMillan
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