Leigh MacMillan Archive — Page 32 of 85

This is a 3D volume rendering of an MRI of a post-mortem heart obtained from a patient with COVID-19, acquired at ultra-high 500 micron spatial resolution.
May 21, 2020

Team uses imaging to study ways the heart is affected by coronavirus

Researchers are using imaging and diagnostic pathology to examine postmortem hearts donated by victims of COVID-19 to gain a better understanding of how the coronavirus that causes COVID-19 affects the heart.

Multiple pipettes dispense pink liquid into the wells of a laboratory microplate.
May 19, 2020

Probing innate immunity

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.

Colorized microscopic view of clusters of purple, rod-shaped bacteria against a green background.
May 14, 2020

The adaptable anthrax bacterium

Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.

Blue toggle switch between red “ON” and black “OFF” labels.
May 5, 2020

A dual-purpose metabolic switch

John York and colleagues have demonstrated that the protein Vip1 is a rare type of bifunctional enzyme: it can both synthesize and destroy key cellular signaling molecules.

Silhouette of a person facing a glowing DNA double helix, overlaid with floating binary digits in a blue-toned digital composition.
April 30, 2020

EHRs, biobanks and Mendelian diseases

Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis.

Stylized 3D rendering of a DNA double helix beside a glowing wireframe Earth, overlaid with molecular formulas, binary digits, and scientific graphics.
April 23, 2020

VUMC joins global effort to explore COVID-19 genetics

Vanderbilt University Medical Center investigators have joined an international genetics effort to make advances as quickly as possible on understanding and treating COVID-19.