Leigh MacMillan

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February 28, 2019

Lighting up colorectal cancer

A nanobeacon imaging agent that binds specifically to colorectal cancer cells may aid the early detection of cancer during colonoscopy.

By Leigh MacMillan
February 28, 2019

Protein loss promotes cell migration

The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.

By Leigh MacMillan
Kareem Mohni, PhD, left, and David Cortez, PhD, have discovered a new DNA repair pathway that guards against genomic mutations.
February 28, 2019

Novel DNA repair mechanism preserves genome integrity: study

Biochemistry investigators at Vanderbilt have discovered a new DNA repair mechanism that prevents gene mutations during DNA replication.

By Leigh MacMillan
February 28, 2019

Evans set for next Discovery Lecture

Ronald Evans, PhD, renowned for his discoveries of nuclear hormone receptors and how they work, will deliver the next Flexner Discovery Lecture on Thursday, March 7.

By Leigh MacMillan
Young Kim, MD, PhD, left, Michael Korrer, PhD, and colleagues are studying a potential new cancer immunotherapy option.
February 21, 2019

Discovery points to new cancer immunotherapy option

An international team involving Vanderbilt researchers has discovered that a new “checkpoint” protein on immune system cells is active in tumors, and that blocking it — in combination with other treatments — is a successful therapeutic approach in mouse models of cancer.

By Leigh MacMillan
February 14, 2019

Probing H. pylori cancer protein

Understanding how a bacterial protein that influences the risk of stomach cancer is produced could guide new strategies for treatment.

By Leigh MacMillan
February 14, 2019

Modulating stress circuits

Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.
By Leigh MacMillan
February 14, 2019

Adhesion protein optimizes border

Matthew Tyska and colleagues have found that an adhesion protein plays a key role in building the intestinal brush border that is essential for absorbing nutrients.
By Leigh MacMillan
February 7, 2019

Black History Month inspires VUMC dermatologist Aleta Simmons’ office door makeover

Adorning the figure’s shoulders, Simmons has placed photos of friends and colleagues in her network of African-American female physicians.
By Leigh MacMillan
January 31, 2019

In utero antibiotics and obesity risk

Maternal antibiotic use during pregnancy was not associated with childhood obesity at age 5, according a national study led by a Vanderbilt pediatrician.
By Leigh MacMillan
January 31, 2019

New target for chronic kidney disease

Preventing the formation of secretory structures that promote scarring in the kidney could offer new therapeutic options for a disease that affects millions of people worldwide.
By Leigh MacMillan
January 31, 2019

Cell death pathway implicated in bone marrow failure

Vanderbilt investigators have linked a specific form of programmed cell death to myelodysplastic syndrome, a type of bone marrow failure.
By Leigh MacMillan
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