Leigh MacMillan

July 15, 2013

Defining patient retention

Vanderbilt researchers propose guidelines for defining patient retention in clinical studies – an important parameter that affects study conclusions and program evaluations.

By Leigh MacMillan
July 12, 2013

Methods for imaging myelin loss

Certain MRI metrics can be used to assess myelin loss in multiple sclerosis, which is important for planning and monitoring therapy.

By Leigh MacMillan
(Joe Howell / Vanderbilt)
July 11, 2013

Model for MADD mitochondrial disease

A zebrafish model of a severe mitochondrial disease will be useful for developing new therapeutic approaches.

By Leigh MacMillan
June 26, 2013

Insights on glaucoma gene mutations

Glaucoma-causing mutations in the gene for myocilin reduce secretion of the protein into the aqueous humor, suggesting a new option for treatment.

By Leigh MacMillan
June 24, 2013

Predicting cancer’s response to therapy

Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding.

By Leigh MacMillan
Heart illustration thumbnail
June 21, 2013

Rhythm response tied to gene variant

A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder.

By Leigh MacMillan
June 20, 2013

Studies outline new model for staph bone infections

Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.
By Leigh MacMillan
June 20, 2013

Disease linked to cell traffic jams

Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface.
By Leigh MacMillan
June 12, 2013

Antacids: risky for premature babies

Antacids that block a certain enzyme pose a risk for a common cardiac problem in premature infants.
By Leigh MacMillan
June 10, 2013

Factor’s yin-yang tumor effects

A factor produced by most malignant cells can both promote and inhibit tumor growth – an insight that is critical to using cancer drugs developed to block this factor.
By Leigh MacMillan
June 6, 2013

Study tracks skin salt’s role in blood pressure control

Clinical pharmacologist Jens Titze, M.D., and his colleagues have identified a new cast of cells and molecules that function in the skin to control sodium balance and blood pressure.
By Leigh MacMillan
June 6, 2013

Matrix member key to insulin resistance

A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.
By Leigh MacMillan