Leigh MacMillan

October 23, 2012

Stomach bug alters tumor suppressor

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.

By Leigh MacMillan
October 18, 2012

Gene regulation found to play role in pulmonary hypertension

New findings from Vanderbilt researchers may explain why only some individuals who have inherited mutations that increase risk for pulmonary hypertension actually develop the disease.

By Leigh MacMillan
October 18, 2012

Setting traps to probe gene function

A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function.

By Leigh MacMillan
October 11, 2012

Amish aid search for Alzheimer’s genes

An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease.

By Leigh MacMillan
October 5, 2012

Host proteins can control HIV infection

The protein APOBEC3G contributes to spontaneous control of HIV-1 in vivo and may provide therapeutic benefits.

By Leigh MacMillan
October 4, 2012

Proteins help flip tumor’s invasive switch

Vanderbilt investigators have identified how two key components of cancer’s invasive “switch” — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.

By Leigh MacMillan
September 25, 2012

Cell entry ports for cold virus

The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells.
By Leigh MacMillan
September 19, 2012

How ‘Jedi’ disposes of dead neurons

The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system.
By Leigh MacMillan
September 13, 2012

Cells with LIP eat their neighbors

A transcription factor called LIP is capable of causing one cell to consume another.
By Leigh MacMillan
September 6, 2012

New doctoral students welcomed

Vanderbilt University Medical Center welcomed 109 new doctoral students into the scientific community last week in the third annual “Simple Beginnings” ceremony.
By Leigh MacMillan
September 6, 2012

Neuronal subtypes in genetic disorder

Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex.
By Leigh MacMillan
August 30, 2012

Targeting new pathways to ease pain

The spinal cord’s neuropeptide Y signaling pathway may be a good target for new pain therapeutics.
By Leigh MacMillan
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