Aliquots - Research Briefs

August 20, 2020

Salt, immune cells and hypertension

Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption.

By Leigh MacMillan
August 20, 2020

A “torque” for tumor blood vessels

Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies.

By Bill Snyder
August 11, 2020

Risk marker for repeat sinus surgery

An inflammatory factor in mucus could be a biomarker of treatment-resistant chronic sinusitis used to determine which patients are at risk for repeat sinus surgery.

By Leigh MacMillan
August 10, 2020

A step toward cancer prevention

A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention.

By Bill Snyder
August 6, 2020

ID of ‘stomach flu’ culprit

Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines.

By Leigh MacMillan
August 6, 2020

The importance of estrogen cycles

Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.

By Sarah E. Glass
July 28, 2020

Post-transplant complication

Vanderbilt researchers conducted the largest analysis to date of a heart complication in children following stem cell transplant. The findings may help guide screening practices to improve outcomes.
By Leigh MacMillan
July 27, 2020

Soy food, metabolism and the microbiome

Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered.
By Sarah E. Glass
July 23, 2020

Stomach bug hit-and-run

The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate.
By Leigh MacMillan
July 23, 2020

Cellular antiviral defenses

A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Vanderbilt researchers have discovered it is also antiviral against DNA viruses.
By Leigh MacMillan
July 14, 2020

New tools to study bioactive lipids

Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction.
By Leigh MacMillan
July 13, 2020

“Nur” target may aid arthritis treatment

Vanderbilt immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells.
By Bill Snyder
July 9, 2020

Recurrent UTIs linked to hidden reservoir

Bacterial invasion of vaginal cells sets up a protective niche and a reservoir for recurrent urinary tract infections, Vanderbilt researchers demonstrated.
By Sarah E. Glass
1 … 21 22 23 24 25 … 92