Aliquots - Research Briefs

July 29, 2019

New role for microtubules in diabetes

Microtubules — part of the cell’s cytoskeleton — regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes.

By Bill Snyder
July 25, 2019

Sex differences in kidney injury

Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.

By Kelsey Herbers
July 24, 2019

Defective transporter linked to autism

A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder.

By Bill Snyder
July 16, 2019

A critical factor for wound healing

Vanderbilt-Ingram Cancer Center scientists have discovered a role for a tumor suppressor protein in skin wound healing.

By Anivarya Kumar
July 15, 2019

Potassium balance and glaucoma

Vanderbilt Eye Institute researchers have discovered that an imbalance in the ionic environment of retinal ganglion cells may contribute to functional impairments in glaucoma.

By Sanjay Mishra
July 11, 2019

New look at atherosclerosis

A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.

By Sanjay Mishra
July 11, 2019

Working memory in psychotic disorders

Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders.
By Kelsey Herbers
June 24, 2019

Early detection of schizophrenia

Inhibited temperament — a tendency to respond to novelty with wariness, fear or caution — may be a risk factor for schizophrenia that could be targeted for preventative interventions.
By Leigh MacMillan
June 24, 2019

Fish oil and cancer prevention

Fish oil supplementation provides a modest but beneficial effect on reducing molecules associated with colorectal cancer development.
By Leigh MacMillan
June 20, 2019

Microbiome links diet to health

Vanderbilt researchers have discovered that the gut microbiome composition modulates how dietary nutrients are metabolized, with potential downstream consequences on metabolic health.
By VUMC News and Communications
June 20, 2019

Potential probe for early ovarian cancer

Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.
By Anivarya Kumar
June 12, 2019

Steroid binding to metabolic enzyme

Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.
By Bill Snyder
June 10, 2019

Cell-cell signals in developing heart

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.
By Leigh MacMillan
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