Aliquots - Research Briefs

April 6, 2023

A ‘supermere’ method for biomarker discovery

Vanderbilt researchers have developed a method for isolating extracellular vesicles and nanoparticles — a complex transport system involved in health and disease — which will improve biomarker discovery and the identification of therapeutic targets.

By Bill Snyder
March 28, 2023

Inflammation implicated in exfoliation syndrome

Computational genetics tools have implicated inflammatory pathways in exfoliation syndrome, the most common cause of secondary glaucoma, which can result in blindness.

By Leigh MacMillan
March 27, 2023

Improving lung nodule diagnosis

Adding blood and imaging biomarkers to a clinical prediction model could improve diagnostic accuracy for the 1.6 million lung nodules detected each year, many through expanded lung cancer screening programs.

By Leigh MacMillan
March 23, 2023

Decoding cell division machinery

Phosphate modification regulates the cell localization of Cdc15, one of the main controllers of cell division, to fine tune the assembly of cell division machinery.

By Caroline Cencer 
March 23, 2023

E. coli uses serine to abide acidity

Vanderbilt researchers have discovered another acid resistance mechanism for UTI-causing E. coli, laying the foundation for targeted antibacterial therapies.

By Cherie Saffold
March 7, 2023

Treating delirium detected in the ED

Higher intensity physical or occupational therapy may be a useful intervention to shorten delirium duration in older hospitalized adults, Vanderbilt researchers recently reported.

By Leigh MacMillan
March 6, 2023

Cell-free hemoglobin in pulmonary hypertension

Cell-free hemoglobin generated by the lungs may be a therapeutic target for treating pulmonary arterial hypertension, Vanderbilt researchers found.
By Leigh MacMillan
March 2, 2023

Sex counts in the brain as seasons change

Photoperiod, or length of day, has sex-specific impacts on dopamine dynamics in the brain, offering insights into sex differences in neuropsychiatric disorders, Vanderbilt researchers report.
By Paul Govern
March 2, 2023

Sex-specific regulation of kidney signals

Links between estrogen signaling and sodium excretion by the kidney could help explain a reduced risk of hypertension in females versus males.
By Kelsey Pinckard
February 21, 2023

Diabetes drug may improve asthma

New biomarker finding strengthens the case for using GLP-1R agonists to treat patients with Type 2 diabetes who also suffer from asthma.
By Sarah E. Glass
February 20, 2023

Probing hellbender health

Understanding how hellbenders — large, fully aquatic salamanders — fight fungal pathogens and disease is important for protecting these unique stream predators; Vanderbilt researchers add new insights.
By Leigh MacMillan
February 16, 2023

Breast cancer genetics: new insights

Largest genetic study of breast cancer to date identifies 222 genetic risk loci, 137 genes and multiple signaling pathways associated with risk, providing important new insights.
By Leigh MacMillan
February 16, 2023

Targeted therapy for neuroendocrine tumors

Cancer therapies that target VEGF receptor appear safe and effective for patients with pancreatic and non-pancreatic neuroendocrine tumors, meta-analysis of phase 2/3 clinical trials demonstrates.
By Kelsey Pinckard
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