New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.

A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease.

To most effectively use electronic health records for research, investigators should query multiple components of the record to identify patients with specific diseases.

A compound acting on serotonin receptors delays a critical step during reovirus cell entry, reducing viral infectivity.

Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory.

A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack.

Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer.