Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory.

A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack.

Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer.

Understanding how macrophage immune cells accumulate in fat tissue and contribute to the pathology of obesity could lead to the development of novel therapeutics for metabolic disorders.

Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.

Understanding how signaling molecules are transported within and out of the cell may help to uncover the causes of certain cancers.

Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease.