A national study led by researchers at Vanderbilt University Medical Center has found that many patients who arrive at the emergency department (ED) with acute heart failure can be safely discharged with self-care guidance and frequent phone appointments, avoiding the need for hospitalization.

A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma.

This spring in the U.S., there were widespread delays in elective health care procedures and screenings. Hospitals, in observance of federal guidelines, were, for a time, conserving beds and protective equipment in preparation for a surge in COVID-19 admissions. And, perhaps on a more prolonged basis, patients in many areas of the country stayed away due to anxiety over catching COVID-19 from other patients or their health care team.

The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances for this rare disease.

The development of the vaccines, monoclonal antibodies and antiviral drugs that ultimately will defeat COVID-19 wouldn’t have been possible had it not been for the unflagging and selfless efforts of a global army of research nurses, laboratory personnel, recruiters and other staff.

Oscar Guillamondegui, MD, MPH, has been named chief of the Division of Trauma and Surgical Critical Care for the Department of Surgery.

Geographically targeted efforts to prevent children being placed in out-of-home care might be possible, Vanderbilt researchers report.