The Robert J. Kleberg Jr. and Helen C. Kleberg Foundation has awarded a $3 million grant to Vanderbilt-Ingram Cancer Center (VICC) investigators in support of VICC’s drug discovery program. The gift awarded over the next three years from the private, San Antonio, Texas-based foundation will enable VICC researchers to pursue the development of new compounds to block the activity of cancer-causing genes and proteins that had previously been considered “undruggable.”

Antidepressant use during pregnancy is common. Fetal exposure to the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) is associated with the life-threatening condition PPHN (persistent pulmonary hypertension of the newborn), but a causal link has not been established.

Arthur L. Brooks, M.D., an innovator of surgical techniques and a mentor to younger orthopaedic surgeons, died Thursday, July 28, at age 91.

During development, neural circuits are remodeled – some synapses are eliminated and others are strengthened – to produce a mature, functional nervous system.

Vanderbilt University Medical Center (VUMC) has once again been named among the nation’s finest providers of specialty care by U.S. News and World Report, and has also been named the No. 1 hospital in Tennessee and the Metro Nashville area.

The 2C-subtype of the serotonin receptor (5HT2C), which binds the neurotransmitter serotonin, plays an important role in regulating food intake and metabolism.

Many patients having surgeries at Monroe Carrell Jr. Children’s Hospital at Vanderbilt are experiencing better recoveries, with less opioids for pain, fewer post-surgery complications and shorter hospital stays due to the work of a medical team that has transformed the way surgeries are handled.