Reporter

Vascular dysfunction during sepsis

Regulation of the enzyme Sirtuin 1 in blood vessel endothelial cells may drive altered metabolism and vascular dysfunction during sepsis, Vanderbilt researchers have discovered.

Vanderbilt study finds that the most common oxygen saturation targets for hospitalized patients appear equally safe and effective

A Vanderbilt study looked at the oxygen saturation target that results in optimal outcomes — number of days alive and free of mechanical ventilation — in 2,500 critically ill adults receiving mechanical ventilation.

By Nancy Humphrey

October 24, 2022

Metabolic signatures of Type 2 diabetes risk

Vanderbilt epidemiologists found 32 blood metabolites associated with obesity and showed that adding these to traditional disease prediction models improves accuracy of determining Type 2 diabetes risk.

By Kelsey Pinckard

October 20, 2022

New target for lung fibrosis

Blocking thromboxane-prostanoid receptor signaling protected animals from lung fibrosis in preclinical models, suggesting a new treatment for IPF — a chronic, progressive lung disorder that often kills within 3-5 years of diagnosis.

By Leigh MacMillan

Yike Li, PhD, and Maria Powell, PhD, examine patient Judit Kiss during a follow-up appointment at the Vanderbilt Voice Center.

October 20, 2022

Implanted stimulator used to treat vocal cord paralysis

Vanderbilt is the only place in the world that has an implantable bilateral pacemaker that can stimulate opening of both vocal folds in patients with bilateral vocal fold paralysis, allowing them to both breathe and speak.

By Craig Boerner

October 20, 2022

Aging beta cells hasten Type 2 diabetes

Vanderbilt investigators have found that aging induces chronic cellular stress in pancreatic beta cells, which could contribute to the development of diabetes as we age.