Research

Bob Coffey, MD
December 8, 2023

Vanderbilt research presented at Cancer Moonshot meet

Vanderbilt Colorectal cancer expert Bob Coffey, MD, was recently invited to present his research to representatives of President Joe Biden’s reignited Cancer Moonshot initiative.

By Bill Snyder
Mariana Byndloss, DVM, PhD, (left), graduate student Catherine Shelton, and their colleagues discovered that beneficial bacteria in the small intestines produce a compound that protects against obesity. (photo by Erin O. Smith)
December 8, 2023

Gut microbiota metabolite protects against obesity: study

Vanderbilt researchers have discovered that beneficial bacteria in the small intestines produce a compound that protects against obesity.

By Leigh MacMillan
December 8, 2023

You missed a few: a better way to count health care-associated influenza cases

The traditional definition of health care-associated influenza leads to gross undercounting, a Vanderbilt study suggests.

By Paul Govern
December 6, 2023

Pasteurization reduces bioactive component of breast milk

Pasteurization of breast milk affects the concentration of osteopontin, a bioactive protein with roles in intestinal, immunological and brain development — suggesting that osteopontin supplementation should be considered when donor milk is provided to preterm infants.

By Leigh MacMillan
December 5, 2023

Role of immunity in kidney injury hints at a potential therapy: study

Targeting the cytokine IL-22 could be a new therapeutic approach to prevent kidney injury caused by drugs or toxins, Vanderbilt researchers have discovered.

By Bill Snyder
December 4, 2023

Study links gene network and pancreatic beta cell defects to Type 2 diabetes

A comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to Type 2 diabetes.

By Leigh MacMillan and Jill Clendening
November 29, 2023

Nonprofits support quest to cure childhood epilepsy

Monica Joanna Elnekaveh was doing everything she could to learn what was causing her 18-month-old daughter’s developmental issues. Her relentless quest to find answers eventually led her to Vanderbilt investigative neurologist Jing-Qiong (Katty) Kang, MD, PhD.
By Bill Snyder
November 21, 2023

Commensal gut bacterium protects from severe intestinal infection

The commensal bacterium Turicibacter sanguinis could be used to protect against severe intestinal infections, Vanderbilt researchers discovered.
By Leigh MacMillan
November 21, 2023

VUMC scientists discover key step to kidney fibrosis

Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure.
By Bill Snyder
November 17, 2023

Tumor antigens key to improving cancer immunotherapy: study

Vanderbilt researchers are working to better design immune therapies that attack tumors without also attacking healthy normal tissue in patients.
By Bill Snyder
November 16, 2023

Nasty microbe H. pylori has Achilles’ heel

Vanderbilt researchers found that an H. pylori enzyme is essential for colonization of the stomach, suggesting it as a promising therapeutic target for H. pylori infection.
By Paul Govern
November 15, 2023

Twelve at Vanderbilt are among world’s highly cited researchers

Twelve current investigators at Vanderbilt University Medical Center and Vanderbilt University are on this year’s list of scientists whose papers have been cited the most frequently by other researchers.
By Bill Snyder
November 15, 2023

Novel C. diff structures are required for infection, offer new therapeutic targets

Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs.
By Leigh MacMillan
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