Research Archive — Page 34 of 194

Stylized side-profile human head with the upper skull rendered transparent to reveal a network-like brain illustration, dissolving into particles against a peach background.
July 8, 2021

Delirium and mortality reexamined

A multicenter study of ICU patients found that in the hospital, delirium was associated with a nearly three-fold increase in risk of death the following day, but after discharge there was no association between delirium and mortality.

Multiple blue-toned sagittal MRI scans of the human brain arranged together, with white technical labels overlaid.
July 8, 2021

Genetics of hydrocephalus

Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition.

Black-and-white stippled head-and-shoulders portrait of a smiling woman with short wavy hair and earrings, identified in the caption as Jennifer Doudna, PhD.
July 7, 2021

Nobel laureate Doudna set for next Discovery Lecture

Nobel laureate Jennifer Doudna, PhD, winner of the 2020 Vanderbilt Prize in Biomedical Science, will deliver the next web-based Discovery Lecture on Thursday, July 22.

July 1, 2021

Preclinical study supports rigosertib as booster to immunotherapy treatment for melanoma

A team of Vanderbilt researchers have shown in a preclinical study that the investigational drug rigosertib could be a potential booster treatment to elicit response to immunotherapies among melanoma patients.

Two hands holding orange prescription pill bottles with white child-resistant caps; one bottle is open with yellow pills visible.
June 22, 2021

Treating metastatic prostate cancer

An indirect comparative effectiveness study using published data suggests that the targeted therapy olaparib should be re-evaluated for treating metastatic prostate cancer.

Conceptual 3D illustration of red, spiked SARS-CoV-2 particles surrounded by Y-shaped ACE2 receptors on a glowing orange background.
June 22, 2021

Combination antibody therapies should retain effectiveness against emerging COVID-19 variants: study

Five monoclonal antibody “cocktails,” including one developed at Vanderbilt University Medical Center (VUMC), are protective in animal studies against several variant strains of COVID-19, according to a report this week in the journal Nature.