Research

3d rendering white blood cells with red blood cells

Putting the brakes on sepsis

An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection.

Records point to drug-drug interaction

Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage.

New breast cancer targets

A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer.

Understanding HDL structure

Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function.

Gene study spots clues to heart risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

Looking beyond the ‘magic bullet’ approach to drug discovery

Vanderbilt scientists have developed a new process that can rapidly and inexpensively identify personalized cancer drugs derived from nature.

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