acute kidney injury

March 7, 2024

Blood mutations increase risk for acute kidney injury: study

A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide.

By Bill Snyder
May 23, 2023

Treating kidney injury before it happens

Pretreatment of an animal model with a novel compound called PHAD reduced kidney injury, suggesting it may be a good candidate for preventing kidney injury in surgical patients.

By Sarah E. Glass
February 2, 2023

Machine learning aids injury prevention in cardiac cath labs

By Paul Govern
Craig Brooks, PhD, and colleagues are studying a molecular mechanism that promotes chronic kidney disease following kidney injury. (photo by Erin O. Smith)
December 15, 2022

Novel therapeutic target identified for chronic kidney disease

Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury.

By Leigh MacMillan
March 17, 2022

Study compares kidney injury risk for COVID, flu patients

A Vanderbilt study found that renin-angiotensin-aldosterone system (RAASi) inhibitor drugs, which are commonly used to regulate high blood pressure, do not disproportionately increase the risk of acute kidney injury (AKI) in patients with COVID-19 compared to patients hospitalized with influenza.

By Emily Stembridge
June 4, 2020

Protecting the injured kidney

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

By Leigh MacMillan
January 28, 2020

Protein levels in urine after acute kidney injury predict future loss of kidney function

High levels of protein in a patient’s urine after acute kidney injury is associated with increased risk of kidney disease progression, Vanderbilt researchers report.
By Kelsey Herbers
October 31, 2019

Acute kidney injury recovery time impacts future risk

Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients.
By Danielle Kopke
October 3, 2019

Study: personalized decision support affects intensive care

For patients in pediatric intensive care who are at high risk for acute kidney injury (AKI), giving clinicians automated decision support during the electronic order entry process increased the rate of blood testing for AKI by 9%.
By Paul Govern
January 31, 2019

New target for chronic kidney disease

Preventing the formation of secretory structures that promote scarring in the kidney could offer new therapeutic options for a disease that affects millions of people worldwide.
By Leigh MacMillan
August 16, 2018

YAP after acute kidney injury

Activation of the signaling protein YAP may be a target for treating acute kidney injury, which affects up to 20 percent of hospitalized patients.
By Sanjay Mishra
January 17, 2018

HDL and kidney injury after surgery

Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.
By Jenelle Grewell
June 8, 2017

New screening model quickly spots acute kidney injury

Researchers at Vanderbilt University Medical Center (VUMC) have developed a screening tool intended to more quickly identify patients with acute kidney injury (AKI).
By VUMC News and Communications