Vanderbilt researchers have discovered that the gut microbiome composition modulates how dietary nutrients are metabolized, with potential downstream consequences on metabolic health.

Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.

Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease.

Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.

A new study published in Neurology reports the drug trofinetide has proven safe and effective in treating core symptoms of Rett syndrome in female children and adolescents.

Using ultrasound to place arterial lines reduces the need for surgical access and improves arterial line location, Vanderbilt researchers have found.