A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered.
Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies.
The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis.
A non-invasive imaging tool could test potential cancer therapies quickly to personalize therapy for patients.
Defects in the production of certain receptors are linked to the pathogenesis of genetic epilepsies and fever-induced seizures.
A person’s mitochondrial gene “signature” could predict risk for diabetic retinopathy and guide early intervention strategies.