The contractile machinery inside tumor cells increases invasive properties, suggesting it might be a good target to inhibit cancer cell spread.

The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

A particular anti-arrhythmia drug provides a targeted treatment for certain forms of atrial fibrillation.

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.

A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine.

A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication.

Understanding how chikungunya virus binds to and enters cells offers a new target for antiviral medications.