Aliquots

March 13, 2014

A new way to target cancer-driver Ras

Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way.

By Leigh MacMillan
March 5, 2014

Web tool speeds pulmonary hypertension discovery

The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis.

By VUMC News and Communications
March 3, 2014

Dismantling staph’s drug resistance

Targeting the enzyme FosB could make antibiotic-resistant staph bacteria sensitive to the antibiotic fosfomycin.

By Leigh MacMillan
February 28, 2014

Imaging guides Alzheimer gene search

Using imaging data, Vanderbilt researchers discovered an association between a gene pair and brain changes in Alzheimer’s disease.

By Leigh MacMillan
February 27, 2014

Probing the pathogenesis of leukemia

A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia.

By Leigh MacMillan
February 12, 2014

Obesity sends immune cells to the brain

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.

By Leigh MacMillan
February 10, 2014

Keeping the beat after heart surgery

Variation in the gene for the beta-1 adrenergic receptor increases the risk that a patient will have an abnormal heart rhythm after cardiac surgery.
By Leigh MacMillan
February 7, 2014

New direction for treating lung cancer

Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.
By Leigh MacMillan
February 6, 2014

Antioxidants promising for rare disorder

The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development.
By Bill Snyder
January 29, 2014

Is healthy obesity possible?

It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity.
By Leigh MacMillan
January 27, 2014

Math models to aid voice disorders

A new computational model of the interactions between vocal folds and the air around them could aid in designing new treatments for voice disorders.
By Leigh MacMillan
January 24, 2014

Probing mysteries of preterm birth

Understanding the relationship between the thinning and rupture of fetal membranes and the presence of bacteria could lead to treatment and prevention strategies for premature birth.
By Leigh MacMillan
January 23, 2014

Human and Helicobacter co-evolution

By VUMC News and Communications