Charles Hong

Pediatric health conditions, their treatments and the related stress hinder the prefrontal cortex, which is the region of the brain associated with learning, memory and behavior. (istock)
September 20, 2017

Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy.

By VUMC News and Communications
July 3, 2017

NOTCH1 role in heart development

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition.

By VUMC News and Communications
tiny petri dishes with wires in them
February 22, 2017

Organ-on-a-chip mimics heart’s biomechanical properties

Scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart’s amazing biomechanical properties in order to study cardiac disease, develop heart drugs.

By VUMC News and Communications
ekg results
January 14, 2016

New method aids heart disease studies, drug discovery efforts

A team of Vanderbilt investigators developed a new method for rapidly generating heart muscle cells from stem cells.

By Leigh MacMillan
December 10, 2015

New lead for ovarian cancer treatment

Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer.

By VUMC News and Communications
October 1, 2015

Collaboration seeks to develop new therapies for bone, other diseases

La Jolla Pharmaceutical Co. and Vanderbilt University have signed a research and license agreement covering Vanderbilt’s research program and intellectual property rights related to compounds that block bone morphogenetic protein (BMP) type-I receptors. The compounds have therapeutic potential in a broad range of diseases, including rare genetic disorders.

By Leigh MacMillan
July 10, 2015

Delivering cells for heart repair

A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair.
By Leigh MacMillan
April 3, 2015

Cancer signaling pathway blocker

Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer.
By VUMC News and Communications
August 14, 2014

Growth factor blockade targets breast tumors

Inhibition of BMP growth factor signaling reduces breast tumor burden and metastasis.
By VUMC News and Communications
September 18, 2013

Fishing for new anti-cancer drugs

Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug.
By Leigh MacMillan
April 18, 2013

Vanderbilt’s Hong, Niswender elected to ASCI

Charles Hong, M.D., Ph.D., and Kevin Niswender, M.D., Ph.D., have been elected to membership in the American Society of Clinical Investigation (ASCI), one of the nation’s most respected medical honor societies.
By Bill Snyder
December 8, 2011

Move out, cholesterol

Compounds developed at Vanderbilt could offer a whole new way to treat atherosclerosis.
By Leigh MacMillan