Department of Biochemistry

Grant bolsters pancreatic cancer drug discovery efforts

The Lustgarten Foundation has awarded a $1.5 million Research Investigator Grant to Stephen Fesik, Ph.D., professor of Biochemistry, Pharmacology and Chemistry, for research designed to discover new drugs for the treatment of pancreatic cancer.

Genome-editing pioneer next up in Discovery Lecture series

Jennifer Doudna, Ph.D., recipient of a 2015 Breakthrough Prize in Life Sciences, will deliver the next Flexner Discovery Lecture on Thursday, Jan. 8.

VU study creates new road map for cellular activity

Human cells are constructed in large part from proteins whose activity can be altered by the incorporation of oxygen in what are known as redox modifications.

Ascano seeks to shed light on cellular stress response

Ebola. Chikungunya. Influenza. What’s to be done about these headline-grabbing, debilitating, often lethal viruses?

Repair protein’s DNA recognition motif

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.

Bypassing DNA damage

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.

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