Department of Pharmacology

Lecture explores efforts to move pharmacogenetics into the clinic

Preemptive genotyping: It sounds like a surprise attack, and it is.

Cancer signaling pathway blocker

Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer.

Pharmacogenomics expert set for Wilkinson Lecture

Mary Relling, Pharm.D., chair of the Department of Pharmaceutical Sciences at St. Jude Children’s Research Hospital in Memphis, will deliver this year’s Grant R. Wilkinson Distinguished Lecture in Clinical Pharmacology on Thursday, April 9.

New view of dopamine heteromers

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

Does fish oil help prevent A-fib?

Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility.

Heart illustration thumbnail

Atrial disease and hypertension links

New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

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