Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders.

To explore how fear becomes entrenched, VUMC researchers traveled down the precise neuronal pathways in the brains of mice that trigger fear responses, and which normally extinguish the behaviors once the danger has passed.

Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis.

Vanderbilt Psychiatric Hospital has opened a new inpatient unit focused primarily on patients in the early stage of a psychotic disorder and on patients who need the most comprehensive diagnostic clarity and close monitoring.

A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder.

Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders.

Inhibited temperament — a tendency to respond to novelty with wariness, fear or caution — may be a risk factor for schizophrenia that could be targeted for preventative interventions.