New findings about proteins involved in DNA repair are important for understanding why some cancers are more or less resistant to certain therapies.

New findings open opportunities to understand mechanisms of DNA repair for a toxic form of DNA damage.

Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis.

New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state.

Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome.