Vanderbilt investigators have combined next-generation sequencing technologies and bioinformatics analyses to screen for genome-wide genetic mutations associated with drug resistance in a series of lung cancer cell lines.

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural “endocannabinoids” without gastrointestinal side effects, Vanderbilt University scientists will report next week.

A study of cognitive complaints in older adults showed that memory concerns from both the patient and an informant was most predictive of converting to Alzheimer’s disease or dementia within three years.

Nephrologist William Fissell IV, M.D., associate professor of Medicine and Biomedical Engineering, is intent on creating and mass-producing an implantable bioartificial kidney that can transform quality of life and prospects for survival for people with chronic kidney disease who would otherwise be forced onto dialysis.

A three-year study that evaluated the effectiveness of a training program designed to enhance autism spectrum disorder identification and assessment within community pediatric settings was released this week in the journal Autism.

A team of Vanderbilt researchers has provided important validation of maps of the brain at rest that may offer insights into changes in the brain that occur in neurological and psychiatric diseases.