gastric cancer

July 7, 2023

Study reveals new clue to gastric cancer

Researchers at Vanderbilt University Medical Center have uncovered evidence of fibroblast cells’ direct involvement in the development of gastric cancer.

By Bill Snyder
March 23, 2023

Goldenring’s gastrointestinal research contributions lauded

Vanderbilt’s James Goldenring, MD, PhD, has been honored by the American Gastroenterological Association for making significant contributions to understanding gastrointestinal disease.

By Bill Snyder
November 10, 2022

Gastric Cancer Foundation funds Eunyoung Choi research

The Gastric Cancer Foundation has awarded a one-year $100,000 research grant to Eunyoung Choi, PhD, to support her efforts to find a way to disrupt the transformation of dysplastic stem cells into stomach cancer.

By Bill Snyder
Eunyoung Choi, PhD, James Goldenring, MD, PhD, and colleagues are studying the development of cancer in the stomach and esophagus.
September 1, 2022

Grant supports research to study gastric cancer origins

Vanderbilt researchers have received $5 million in funding from a new initiative by the National Cancer Institute that aims to define how gastric and gastroesophageal junction adenocarcinomas form and evolve at the cellular level.

By Tom Wilemon
June 23, 2022

Study reveals how gastric cancer forms, suggests preventive treatment

Eunyoung Choi, PhD, assistant professor of Surgery, and colleagues identified for the first time that Trop2+/CD133+/CD166+ dysplastic stem cells are a key source of clonal evolution of dysplasia to multiple types of gastric cancer.

By Tom Wilemon
June 2, 2022

Choi, Short receive AGA Research Foundation Awards

Two Vanderbilt researchers have received awards from the AGA Foundation, the charitable arm of the American Gastroenterological Association.

By Tom Wilemon
April 7, 2022

New prognosis predictor and target for gastric cancer

The protein CGA — a subunit of glycoprotein hormones — is a biomarker that predicts chemoresistance in gastric cancer and could be targeted along with EGFR to restore chemosensitivity.
By Sarah E. Glass
January 17, 2022

H. pylori, lipid loss and stomach cancer

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered.
By Leigh MacMillan
December 13, 2021

Oral microbes and gastric cancer

Studies in three large population cohorts that include Asian, African American and European American people support a role for the oral microbiota — the collection of microbial species in the mouth — in gastric cancer development.
By Leigh MacMillan
October 14, 2021

New marker for metaplasia

A protein that transports water, called aquaporin 5, is expressed by cells undergoing changes that may increase risk for gastric cancer development, Vanderbilt researchers discovered.
By Bill Snyder
August 4, 2021

Study finds genetic factor undermines H. pylori treatment

Helicobacter pylori, a stomach-dwelling bacterium, is a strong risk factor for gastric cancer, peptic ulcers and other debilitating gastrointestinal disorders. Yet efforts to eradicate it using a combination of antibiotics and proton pump inhibitors (PPIs), which suppress gastric acid production, often fail.
By Bill Snyder
August 6, 2020

Study gauges specific site stomach cancer risks among ethnic groups

Non-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic white Americans. A new study breaks down this risk according to specific ethnicities and locations within the stomach.
By Tom Wilemon
July 23, 2020

Stomach bug hit-and-run

The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate.
By Leigh MacMillan
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